WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
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DOI: 10.1126/sciadv.1700090
Abstract: WNT antagonism displays marked synergy with taxane chemotherapy and reverses taxane-induced enrichment of cancer stem cells. The WNT pathway mediates intercellular signaling that regulates cell fate in both normal development and cancer. It is widely… read more here.
Keywords: wnt antagonists; activity taxanes; mitotic cell; wnt ... See more keywords