Pannexin 1 channels control CaV1.2 channel activity and vascular reactivity in diabetic hyperglycemia
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DOI: 10.1152/physiol.2023.38.s1.5731650
Abstract: Vascular complications are major causes of morbidity and mortality in diabetic patients. Recently, our group identified a novel purinergic signaling pathway involving the AKAP5/P2Y11/AC5/PKA/CaV1.2 protein network in arterial myocytes that is activated upon diabetic hyperglycemia… read more here.
Keywords: vascular reactivity; diabetic hyperglycemia; arterial myocytes; activity vascular ... See more keywords