Articles with "activity zebrafish" as a keyword



Novel mRNA therapy restores GALT protein and enzyme activity in a zebrafish model of classic galactosemia

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Published in 2022 at "Journal of Inherited Metabolic Disease"

DOI: 10.1002/jimd.12512

Abstract: Messenger RNA (mRNA) has emerged as a novel therapeutic approach for inborn errors of metabolism. Classic galactosemia (CG) is an inborn error of galactose metabolism caused by a severe deficiency of galactose‐1‐phosphate:uridylyltransferase (GALT) activity leading… read more here.

Keywords: enzyme activity; zebrafish model; activity; activity zebrafish ... See more keywords

Effects of pharmaceuticals and personal care products (PPCPs) on multixenobiotic resistance (MXR) related efflux transporter activity in zebrafish (Danio rerio) embryos.

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Published in 2017 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2016.10.022

Abstract: Certain ATP binding cassette (ABC) transporter proteins, such as zebrafish Abcb4, are efflux pumps acting as a cellular defence against a wide range of different, potentially toxic chemical compounds thus mediating so called multixenobiotic resistance… read more here.

Keywords: mxr; atpase; rhodamine 123; activity zebrafish ... See more keywords

Soy-Derived Equol Induces Antioxidant Activity in Zebrafish in an Nrf2-Independent Manner

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23095243

Abstract: Antioxidant effects of soy-derived isoflavones are predicted to be mediated by the Keap1-Nrf2 pathway. Recently, we constructed an assay system to evaluate the antioxidant effects of dietary phytochemicals in zebrafish and revealed a relationship between… read more here.

Keywords: antioxidant effects; antioxidant activity; nrf2; soy derived ... See more keywords

The Study of Myo-Inositol’s Anxiolytic Activity on Zebrafish (Danio rerio)

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Published in 2024 at "Nutrients"

DOI: 10.3390/nu16131997

Abstract: Introduction: Myo-inositol (MI) is the most abundant inositol found in nature. To date MI supplementation is reported to be effective in the treatment of polycystic ovary syndrome, it is also suggested to alleviate the symptoms… read more here.

Keywords: myo inositol; activity; inositol anxiolytic; study myo ... See more keywords