Articles with "actl6a occupancy" as a keyword



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Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma.

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Published in 2021 at "Molecular cell"

DOI: 10.1016/j.molcel.2021.10.005

Abstract: Mammalian SWI/SNF (BAF) chromatin remodelers play dosage-sensitive roles in many human malignancies and neurologic disorders. The gene encoding the BAF subunit actin-like 6a (ACTL6A) is amplified early in the development of many squamous cell carcinomas… read more here.

Keywords: squamous cell; baf; actl6a occupancy; increased actl6a ... See more keywords