Binding of alpha-ACTN4 to EGF receptor enables its rapid phosphorylation
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06011
Abstract: Alpha-ACTN4, a member of alpha-actinin family is critical for cell motility through its regulated binding of actin filaments. We previously found that EGF exposure of cells triggers the tyrosyl-phosphorylation of ACTN4 in fibroblasts that dramatically… read more here.
Keywords: actn4 egf; phosphorylation; actn4; egf receptor ... See more keywords
The FSGS protein actinin-4 interacts with NKCC2 to regulate thick ascending limb NaCl reabsorption
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Physiology - Renal Physiology"
DOI: 10.1152/ajprenal.00119.2024
Abstract: In the kidney, the thick Ascending Limb (TAL) of the loop of Henle is crucial for NaCl homeostasis and blood pressure regulation. In animal models of salt-sensitive hypertension, NaCl reabsorption via the apical Na+/K+/2Cl cotransporter… read more here.
Keywords: physiology; thick ascending; nacl reabsorption; actn4 ... See more keywords