ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension
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DOI: 10.1126/scitranslmed.aaz5660
Abstract: ACTRIIA-Fc, an activin and GDF8/11 ligand trap, improves hemodynamics and exerts antiremodeling effects in experimental pulmonary hypertension. Remedying pulmonary vascular remodeling Alterations in bone morphogenetic protein, growth and differentiation factor (GDF), and transforming growth factor–β… read more here.
Keywords: protein; bmp signaling; activin; pulmonary hypertension ... See more keywords