Safety and Efficacy of Sovateltide (IRL-1620) in a Multicenter Randomized Controlled Clinical Trial in Patients with Acute Cerebral Ischemic Stroke
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DOI: 10.1007/s40263-020-00783-9
Abstract: Background Sovateltide (IRL-1620, PMZ-1620), an endothelin-B receptor agonist, has been previously shown to increase cerebral blood flow, have anti-apoptotic activity and produce neurovascular remodeling when administered intravenously following acute cerebral ischemic stroke in rats. Its… read more here.
Keywords: cerebral ischemic; ischemic stroke; acute cerebral; group ... See more keywords
Engineering advanced neural tissue constructs to mitigate acute cerebral inflammation after brain transplantation in rats.
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DOI: 10.1016/j.biomaterials.2018.11.031
Abstract: Stroke, traumatic brain injuries, and other similar conditions often lead to significant loss of functional brain tissue and associated disruption of neuronal signaling. A common strategy for replacing lost neurons is the injection of dissociated… read more here.
Keywords: acute cerebral; inflammation; tissue; transplantation ... See more keywords
Epileptic spasms secondary to acute cerebral and cerebellar encephalitis
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Development"
DOI: 10.1016/j.braindev.2017.11.006
Abstract: BACKGROUND Patients with infection-related acute encephalitis sometimes develop epilepsy in the chronic phase of the disease. Patients with postencephalitic epilepsy usually develop partial seizures due to the lesions generated by the encephalitis. We report a… read more here.
Keywords: acute cerebral; months onset; epileptic spasms; encephalitis ... See more keywords
Hyperforin protects against acute cerebral ischemic injury through inhibition of interleukin-17A-mediated microglial activation
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2017.08.023
Abstract: Hyperforin, a pharmacologically active component of the medicinal plant Hypericum perforatum (St. John's wort), has been shown to be neuroprotective against acute ischemic stroke. However, the underlying mechanisms are still unclear and need to be… read more here.
Keywords: acute cerebral; interleukin 17a; activation; injury ... See more keywords
Extract of Naotaifang, a compound Chinese herbal medicine, protects neuron ferroptosis induced by acute cerebral ischemia in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of integrative medicine"
DOI: 10.1016/j.joim.2020.01.008
Abstract: OBJECTIVE Our previous research showed that Naotaifang (a compound traditional Chinese herbal medicine) extract (NTE) has clinically beneficial effects on neurological improvement of patients with acute cerebral ischemia. In this study, we investigated whether NTE… read more here.
Keywords: medicine; acute cerebral; naotaifang compound; cerebral ischemia ... See more keywords
NGF/FAK signal pathway is implicated in angiogenesis after acute cerebral ischemia in rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.02.023
Abstract: Neurogenesis in the cerebral infarction after an ischemic event is important to the rehabilitation of patients. However, the mechanism of angiogenesis around cerebral ischemia is not clear. Our study designed to test whether the nerve… read more here.
Keywords: acute cerebral; ngf fak; cerebral ischemia; pathway ... See more keywords
Risk Factors for Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Cerebral Infarction: A Retrospective Single-Center Study.
Sign Up to like & getrecommendations! Published in 2017 at "World neurosurgery"
DOI: 10.1016/j.wneu.2017.01.091
Abstract: OBJECTIVE To investigate the risk factors for hemorrhagic transformation (HT) after intravenous thrombolysis using a recombinant tissue plasminogen activator (r-tPA) in acute cerebral infarction. METHODS Patients with acute cerebral infarction receiving r-tPA thrombolysis in Shanghai… read more here.
Keywords: acute cerebral; cerebral infarction; thrombolysis; risk factors ... See more keywords
Diagnostic value of non-contrast brain computed tomography in the evaluation of acute cerebral venous thrombosis
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DOI: 10.1038/s41598-020-57867-1
Abstract: Acute cerebral vein thrombosis is usually seen as increased attenuation in brain non-contrast computed tomography. It is so helpful to define measurable parameters for subjective evaluation of sinus thrombosis in non-enhanced brain computed tomography, especially… read more here.
Keywords: acute cerebral; computed tomography; ratio; thrombosis ... See more keywords
Fabry disease with acute cerebral infarction onset in a young patient
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DOI: 10.1097/cm9.0000000000000089
Abstract: 6 2.3–4.1mmol/L), leukocytes 23 10 /L (normal: [0–8] To the Editor: Fabry disease (FD) is a recessive X-linked hereditary disease. The onset age of the disease is in 10/L), cerebrospinal fluid immunoglobulin IgG 68mg/L children… read more here.
Keywords: fabry disease; acute cerebral; cerebral infarction; infarction onset ... See more keywords
Metoprolol and Nebivolol Prevent the Decline of the Redox Status of Low-Molecular-Weight Aminothiols in Blood Plasma of Rats During Acute Cerebral Ischemia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000616
Abstract: Abstract: Cerebral ischemia has previously been shown to cause a systemic decrease in levels of the reduced forms of low-molecular-weight aminothiols [cysteine (Cys), homocysteine (Hcy), and glutathione (GSH)] in blood plasma. In this study, we… read more here.
Keywords: acute cerebral; blood plasma; cerebral ischemia; ischemia ... See more keywords
Salvianolate injection in the treatment of acute cerebral infarction
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DOI: 10.1097/md.0000000000012374
Abstract: Abstract To evaluate the effectiveness and safety of Salvianolate injection (SI) in the treatment of acute cerebral infarction (ACI). We electronically searched databases including PubMed, The Cochrane Library, EMBASE, Chinese Biomedical Literature Database, Chinese National… read more here.
Keywords: medicine; injection treatment; acute cerebral; salvianolate injection ... See more keywords