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Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23105347

Abstract: Neuroinflammation underlies neurodegenerative diseases. Herein, we test whether acute colon inflammation activates microglia and astrocytes, induces neuroinflammation, disturbs neuron intrinsic electrical properties in the primary motor cortex, and alters motor behaviors. We used a rat… read more here.

Keywords: inflammation; motor; acute colon; colon inflammation ... See more keywords