Serum troponin is elevated in acute decompensation and acute-on-chronic liver failure and is associated with severity of liver disease and short-term mortality.
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DOI: 10.1080/00365521.2022.2131333
Abstract: BACKGROUND The role of high sensitive cardiac Troponin (hs-cTn) in patients with liver cirrhosis (LC) and liver-related acute events is not well established. AIM To assess the prognostic performance of hs-cTn I in acute decompensation… read more here.
Keywords: liver; mortality; acute chronic; acute decompensation ... See more keywords
Acute-on-chronic liver failure: a global disease
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DOI: 10.1136/gutjnl-2020-323973
Abstract: Acuteonchronic liver failure (ACLF) is a frequent complication in hospitalised patients with liver cirrhosis. A large body of data has been published in recent years, demonstrating that acute decompensation constitutes a dramatic turning point in… read more here.
Keywords: acute decompensation; metaanalysis; cirrhosis; disease ... See more keywords
Vulnerability to recurrent episodes of acute decompensation/acute-on-chronic liver failure characterizes those triggered by indeterminate precipitants in patients with liver cirrhosis
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DOI: 10.1371/journal.pone.0250062
Abstract: Background Acute decompensation (AD) of liver cirrhosis (LC) and subsequent acute-on-chronic liver failure (ACLF) are fatal and impair quality of life. Insufficient knowledge of the highly heterogeneous natural history of LC, including decompensation, re-compensation, and… read more here.
Keywords: acute decompensation; acute; liver; recurrent ... See more keywords
Impact of acute decompensation on the prognosis of patients with hepatocellular carcinoma
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DOI: 10.1371/journal.pone.0261619
Abstract: Background/Aims Organ failure in patients with acute decompensation (AD) is a defining characteristic of acute-on-chronic liver failure (ACLF). However, the clinical features of AD during the long-term clinical course of hepatocellular carcinoma (HCC) are still… read more here.
Keywords: hepatocellular carcinoma; prognosis; hcc; impact ... See more keywords
Diagnostic and prognostic significance of cell death markers in patients with cirrhosis and acute decompensation
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DOI: 10.1371/journal.pone.0263989
Abstract: Background The transition from compensated to decompensated liver cirrhosis is a hallmark of disease progression, however, reliable predictors to assess the risk of decompensation in individual patients from routine diagnostics are lacking. Here, we characterize… read more here.
Keywords: decompensation; liver disease; acute decompensation; biochemistry ... See more keywords
Therapeutic possibilities of gut microbiota modulation in acute decompensation of liver cirrhosis
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DOI: 10.4254/wjh.v15.i4.525
Abstract: The formation of liver cirrhosis (LC) is an unfavorable event in the natural history of chronic liver diseases and with the development of portal hypertension and/or impaired liver function can cause a fatal outcome. Decompensation… read more here.
Keywords: decompensation; liver cirrhosis; gut microbiota; modulation ... See more keywords