Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25444
Abstract: Liver disease is a common cause of non‐AIDS morbidity and mortality in people living with HIV (PLHIV), but the prevalence and significance of liver function test (LFT) abnormalities in early HIV infection is unknown. This… read more here.
Keywords: hiv infection; liver function; function test; infection ... See more keywords
Determinants of suboptimal CD4+ T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV‐1 infection
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DOI: 10.1002/jia2.25585
Abstract: Up to 30% of individuals treated with antiretroviral therapy (ART) during chronic HIV fail to recover CD4 counts to >500 cells/mm3 despite plasma viral suppression. We investigated the frequency and associations of suboptimal CD4 recovery… read more here.
Keywords: antiretroviral therapy; hiv infection; hiv; suboptimal cd4 ... See more keywords
Circulating mitochondrial DNA and LPS-binding protein but not bacterial DNA are increased in acute HIV infection.
Sign Up to like & getrecommendations! Published in 2020 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2020.0098
Abstract: Microbial translocation has been suggested as a major driver of chronic immune activation HIV infection. Thus, we compared the extent of microbial translocation in patients with acute HIV infection and patients followed after CD4-guided structured… read more here.
Keywords: acute hiv; hiv infection; lps binding; dna ... See more keywords
Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection
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DOI: 10.1093/cid/ciw683
Abstract: Background. Serious non-AIDS events cause substantial disease and death despite human immunodeficiency virus (HIV) suppression with antiretroviral therapy (ART). Biomarkers of inflammation, coagulation cascade activation, and fibrosis predict these end-organ events. We aimed to determine… read more here.
Keywords: hiv infection; art; hiv; acute hiv ... See more keywords
1272. A Routine, HIV and HCV Testing and Treatment Program in a Large, Multi-Campus Emergency Department Finds High Prevalence of Acute HIV and Chronic Hepatitis C
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1105
Abstract: Abstract Background One in seven people living with HIV in the United States are unaware of their serostatus. Approximately 11,280 annual HIV infections (30.2%) are caused by this subset of individuals (CDC, 2017). In addition,… read more here.
Keywords: hiv; hcv; hiv hcv; routine hiv ... See more keywords
1276. Human Immunodeficiency Virus (HIV) Diagnostic Limbo: A Retrospective Review of Discordant HIV Test Results in a Large, Academic Health Center Over a 10-Year Period to Guide Clinicians in Distinguishing False-Positive vs. Acute HIV Infection
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1109
Abstract: Abstract Background The Centers for Disease Control and Prevention (CDC) recommends universal HIV screening with a fourth-generation HIV-1/2 antigen–antibody immunoassay followed by an HIV-1/-2 antibody differentiation immunoassay. Discordant results require nucleic acid testing (NAT) to… read more here.
Keywords: discordant; hiv; test; health ... See more keywords
Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome.
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DOI: 10.1093/ofid/ofz367
Abstract: Background Intestinal microbial dysbiosis is evident in chronic HIV-infected individuals and may underlie inflammation that persists even during antiretroviral therapy (ART). It remains unclear, however, how early after HIV infection gut dysbiosis emerges and how… read more here.
Keywords: acute hiv; hiv infection; art; hiv ... See more keywords
Integration of Contact Tracing and Phylogenetics in an Investigation of Acute HIV Infection
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DOI: 10.1097/olq.0000000000000726
Abstract: Background The integration of traditional contact tracing with HIV sequence analyses offers opportunities to mitigate some of the barriers to effective network construction. We used combined analyses during an outbreak investigation of spatiotemporally clustered acute… read more here.
Keywords: contact tracing; network; integration; investigation ... See more keywords
Brain volumetrics differ by fiebig stage in acute HIV infection.
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DOI: 10.1097/qad.0000000000003496
Abstract: OBJECTIVE People with chronic HIV exhibit lower regional brain volumes compared to people without HIV (PWOH). Whether imaging alterations observed in chronic infection occur in acute HIV infection (AHI) remains unknown. DESIGN Cross-sectional study of… read more here.
Keywords: acute hiv; late fiebig; infection; brain ... See more keywords
Blood and genital fluid viral load trajectories among treated and untreated persons with acute HIV infection in Malawi.
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DOI: 10.1097/qai.0000000000002917
Abstract: BACKGROUND Persons with acute HIV infection (AHI) are highly infectious and responsible for a disproportionate share of incident infections. Immediate antiretroviral therapy (ART) rapidly reduces blood viral loads (VL), but genital VLs after ART initiation… read more here.
Keywords: art; persons acute; malawi; blood ... See more keywords
Immediate treatment of acute HIV in a tertiary healthcare center: bridging gaps in communication using smartphones
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DOI: 10.1111/hiv.12713
Abstract: Early initiation of antiretroviral therapy (ART) during acute HIV infection is associated with favourable clinical and epidemiological outcomes. Barriers to prompt treatment initiation limit the benefits of universal access to ART in Mexico. We sought… read more here.
Keywords: immediate treatment; treatment acute; acute hiv; hiv ... See more keywords