Inhibiting the Piezo1 channel protects microglia from acute hyperglycaemia damage through the JNK1 and mTOR signalling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118667
Abstract: AIM Diabetes is a high-risk factor for neurocognitive dysfunction. Diabetic acute hyperglycaemia accompanied by high osmotic pressure can induce immune cell dysfunction, but its mechanism of action in brain microglia remains unclear. This study aimed… read more here.
Keywords: piezo1; hyperglycaemia; acute hyperglycaemia; jnk1 mtor ... See more keywords
No impact of acute hyperglycaemia on arterial stiffness in the early and late follicular phases of the menstrual cycle in young females
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Physiology"
DOI: 10.1113/ep087899
Abstract: • What is the central question of this study? This is the first study to examine the impact of acute hyperglycaemia on arterial stiffness across the early and late follicular phases of the menstrual cycle.… read more here.
Keywords: impact acute; arterial stiffness; hyperglycaemia; menstrual cycle ... See more keywords