Serum Neurofilament Light and Multiple Sclerosis Progression Independent of Acute Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.47588
Abstract: This cohort study investigates serum neurofilament light concentration as a biomarker associated with disability progression in multiple sclerosis in the absence of acute inflammation. read more here.
Keywords: neurofilament light; progression; acute inflammation; multiple sclerosis ... See more keywords
Xist attenuates acute inflammatory response by female cells
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03500-3
Abstract: Biological sex influences inflammatory response, as there is a greater incidence of acute inflammation in men and chronic inflammation in women. Here, we report that acute inflammation is attenuated by X-inactive specific transcript (Xist), a… read more here.
Keywords: acute inflammation; female; inflammation; inflammatory response ... See more keywords
sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.02.078
Abstract: Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and a pseudoanomeric hydrophobic tail, termed sp2-iminosugar glycolipids (sp2-IGLs), target microglia during neuroinflammatory processes. Here we have synthesized and investigated new variants of sp2-IGLs for their… read more here.
Keywords: acute inflammation; iminosugar glycolipids; sp2 iminosugar; activation ... See more keywords
The Atlas of Inflammation Resolution (AIR).
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2020.100893
Abstract: Acute inflammation is a protective reaction by the immune system in response to invading pathogens or tissue damage. Ideally, the response should be localized, self-limited, and returning to homeostasis. If not resolved, acute inflammation can… read more here.
Keywords: acute inflammation; inflammation resolution; inflammation; air ... See more keywords
The impact of acute inflammation on progression and metastasis in pancreatic cancer animal model.
Sign Up to like & getrecommendations! Published in 2018 at "Surgical oncology"
DOI: 10.1016/j.suronc.2017.11.008
Abstract: BACKGROUND The impact of acute inflammation on cancer is unclear. Therefore, we evaluated the impact of acute inflammation on cancer progression in an animal model concerning morphological change as well as molecular features. MATERIAL AND… read more here.
Keywords: acute inflammation; group; inflammation; impact acute ... See more keywords
Hypoalbuminemia in COVID‐19
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13403
Abstract: I read with interest the paper by Wu et al. [1] dealing with the issue of hypoalbuminemia in patients with COVID-19. The authors reported that hypoalbuminemia, expression of disease severity, may be due to pulmonary… read more here.
Keywords: albumin; hypoalbuminemia; acute inflammation; synthesis albumin ... See more keywords
Influence of fitness and age on the endothelial response to acute inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Physiology"
DOI: 10.1113/ep086922
Abstract: What is the central question of the study? What are the effects of age and fitness on the vascular response to acute inflammation in younger and older adults? What is the main finding and its… read more here.
Keywords: acute inflammation; fitness; age; response acute ... See more keywords
Long non-coding RNA expression profiling in the lungs of pulmonary arterial hypertension rats with acute inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Pulmonary Circulation"
DOI: 10.1177/2045894019879393
Abstract: Background We performed RNA-sequencing to investigate the changes and expression profiles in long non-coding RNAs (lncRNAs) and their potential functional roles in the lungs of pulmonary arterial hypertension rats responding to acute inflammation. Methods To… read more here.
Keywords: pulmonary arterial; arterial hypertension; acute inflammation; hypertension rats ... See more keywords
Intestinal IL-33 promotes platelet activity for neutrophil recruitment during acute inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2021013474
Abstract: The peripheral serotonin (5-HT) is mainly generated from the gastrointestinal tract, and taken up and stored by platelets in the circulation. While the gut is recognized as a major immune organ, how intestinal local immune… read more here.
Keywords: acute inflammation; intestinal promotes; physiology; inflammation ... See more keywords
Differential antibacterial control by neutrophil subsets.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2017015578
Abstract: Neutrophils comprise a heterogeneous population of cells essential for bacterial eradication, and defects in neutrophil function are associated with increased susceptibility to infection. In this study, neutrophils from healthy controls were shown to prevent bacterial… read more here.
Keywords: differential antibacterial; acute inflammation; control neutrophil; antibacterial control ... See more keywords
Prolonged immune alteration following resolution of acute inflammation in humans
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DOI: 10.1371/journal.pone.0186964
Abstract: Acute inflammation is an immediate response to infection and injury characterised by the influx of granulocytes followed by phagocytosing mononuclear phagocytes. Provided the antigen is cleared and the immune system of the host is fully… read more here.
Keywords: resolution; post resolution; prolonged immune; acute inflammation ... See more keywords