Off-Label Use of Tenecteplase for the Treatment of Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.4506
Abstract: Key Points Question How does the use of tenecteplase compare with the use of alteplase in the clinical outcomes of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis? Findings In this systematic review and… read more here.
Keywords: use tenecteplase; tenecteplase; acute ischemic; use ... See more keywords
Effectiveness of a Quality Improvement Intervention on Reperfusion Treatment for Patients With Acute Ischemic Stroke: A Stepped-Wedge Cluster Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2023.16465
Abstract: Key Points Question What is the effect of a problem-oriented, culturally adapted, targeted quality improvement intervention on reperfusion therapy, including intravenous thrombolysis or endovascular thrombectomy, for acute ischemic stroke in China? Findings In this stepped-wedge… read more here.
Keywords: acute ischemic; reperfusion; ischemic stroke; quality improvement ... See more keywords
Effect of General Anesthesia and Conscious Sedation During Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.4474
Abstract: Importance Endovascular therapy (EVT) is the standard of care for select patients who had a stroke caused by a large vessel occlusion in the anterior circulation, but there is uncertainty regarding the optimal anesthetic approach… read more here.
Keywords: ischemic stroke; trial; clinical outcomes; infarct growth ... See more keywords
Quantification of Penumbral Volume in Association With Time From Stroke Onset in Acute Ischemic Stroke With Large Vessel Occlusion.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.0265
Abstract: Importance The benefit of reperfusion therapies for acute ischemic stroke decreases over time. This decreasing benefit is presumably due to the disappearance of salvageable ischemic brain tissue (ie, the penumbra). Objective To study the association… read more here.
Keywords: time; occlusion; volume; acute ischemic ... See more keywords
Symptomatic Intracranial Hemorrhage With Tenecteplase vs Alteplase in Patients With Acute Ischemic Stroke: The Comparative Effectiveness of Routine Tenecteplase vs Alteplase in Acute Ischemic Stroke (CERTAIN) Collaboration.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.1449
Abstract: Importance Symptomatic intracranial hemorrhage (sICH) is a serious complication of stroke thrombolytic therapy. Many stroke centers have adopted 0.25-mg/kg tenecteplase instead of alteplase for stroke thrombolysis based on evidence from randomized comparisons to alteplase as… read more here.
Keywords: tenecteplase; acute ischemic; tenecteplase alteplase; stroke ... See more keywords
rt‐PA with remote ischemic postconditioning for acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.713
Abstract: To investigate the feasibility and safety of remote ischemic postconditioning (RIPC) in acute ischemic stroke patients after intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis (IVT). read more here.
Keywords: ischemic stroke; ischemic postconditioning; acute ischemic; remote ischemic ... See more keywords
Hydrogen‐Powered Microswimmers for Precise and Active Hydrogen Therapy Towards Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202009475
Abstract: Biodegradable microswimmers offer great potential for minimally invasive targeted therapy due to their tiny scale, multifunctionality, and versatility. However, most of the reported systems focused on the proof‐of‐concept on the in vitro level. Here, the… read more here.
Keywords: acute ischemic; hydrogen powered; therapy; hydrogen ... See more keywords
Annexin V‐Modified Platelet‐Biomimetic Nanomedicine for Targeted Therapy of Acute Ischemic Stroke
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DOI: 10.1002/adhm.202200416
Abstract: Thromboembolic stroke is typically characterized by the activation of platelets, resulting in thrombus in the cerebral vascular system, leading to high morbidity and mortality globally. Intravenous thrombolysis by tissue plasminogen activator (tPA) administration within 4.5… read more here.
Keywords: platelet biomimetic; acute ischemic; platelet; ischemic stroke ... See more keywords
Intravenous Thrombolysis with Tenecteplase for the Treatment of Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26445
Abstract: Intravenous thrombolysis (IVT) with tenecteplase has been associated with better clinical outcomes in acute ischemic stroke (AIS) patients with confirmed large vessel occlusions compared to IVT with alteplase. However, the utility of tenecteplase for the… read more here.
Keywords: tenecteplase; acute ischemic; intravenous thrombolysis; tenecteplase treatment ... See more keywords
Perioperative Acute Ischemic Stroke in Patients with Atrial Fibrillation.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of neurology"
DOI: 10.1002/ana.26678
Abstract: OBJECTIVE Anticoagulation therapy is commonly interrupted in patients with atrial fibrillation (AF) for elective procedures. However, the risk factors of acute ischemic stroke (AIS) during the periprocedural period remain uncertain. We performed a nationwide analysis… read more here.
Keywords: patients atrial; acute ischemic; risk factors; risk ... See more keywords
Clinical characteristics and risk score for poor clinical outcome of acute ischemic stroke patients treated with intravenous thrombolysis therapy
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1251
Abstract: Tissue plasminogen activator (t‐PA) is an effective therapy for acute ischemic stroke, but some patients still have poor clinical outcome. In this study, we investigated clinical characteristics of stroke patients and determined predictors for poor… read more here.
Keywords: ischemic stroke; poor clinical; acute ischemic; stroke patients ... See more keywords