Trans‐Synaptic Degeneration Following Acute Optic Neuritis in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26529
Abstract: To explore longitudinal changes in brain volumetric measures and retinal layer thicknesses following acute optic neuritis (AON) in people with multiple sclerosis (PwMS), to investigate the process of trans‐synaptic degeneration, and determine its clinical relevance. read more here.
Keywords: acute optic; following acute; trans synaptic; optic neuritis ... See more keywords
O9 Early macular atrophy at optical coherence tomography is predicted by visual evoked potentials and precedes peripapillary neurodegeneration after acute optic neuritis
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2017.07.020
Abstract: Background Demyelination and axonal loss following acute optic neuritis (AON) can be respectively measured as delayed visual evoked potentials (VEPs) and as reduced thickness of retinal nerve fiber (RNFL) and ganglion cell-inner plexiform layer (GCL-IPL)… read more here.
Keywords: gcl; gcipl; neurodegeneration; acute optic ... See more keywords
Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases
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DOI: 10.1371/journal.pone.0184927
Abstract: Purpose Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated… read more here.
Keywords: pct; demyelinating diseases; optic neuritis; hypoperfusion ... See more keywords
Early predictors of visual and axonal outcomes after acute optic neuritis
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DOI: 10.3389/fneur.2022.945034
Abstract: Background Predicting long-term visual outcomes and axonal loss following acute optic neuritis (ON) is critical for choosing treatment. Predictive models including all clinical and paraclinical measures of optic nerve dysfunction following ON are lacking. Objectives… read more here.
Keywords: axonal loss; acute optic; optic nerve; loss ... See more keywords