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   Articles with "acute oral" as a keyword



Acute Oral Toxicity of Nonfluorinated Fire‐Fighting Foams to Northern Bobwhite Quail (Colinus virginianus)

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recommendations! Published in 2022 at "Environmental Toxicology and Chemistry"

DOI: 10.1002/etc.5398

Abstract: Long‐chain per‐ and poly‐fluoroalkyl substances (PFAS) have been the active ingredients in firefighting foams for more than 50 years. Due to their extreme persistence, regulatory agencies are concerned about their potential adverse environmental and health… read more here.

Keywords: quail; oral toxicity; fighting foams; fire fighting ... See more keywords

Prebiotic properties, antioxidant activity, and acute oral toxicity of xylooligosaccharides derived enzymatically from corncob

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recommendations! Published in 2021 at "Food bioscience"

DOI: 10.1016/j.fbio.2021.100895

Abstract: Abstract In this study, corncob xylooligosaccharides (corncob-XOS) were prepared enzymatically, and their beneficial effects, compared to commercial prebiotics, including fructooligosaccharides (FOS), gentiooligosaccharides (GTO), inulin, isomaltooligosaccharides (IMO), lactulose, and commercial xylooligosaccharides (commercial-XOS), were assessed. The prebiotic… read more here.

Keywords: oral toxicity; corncob xos; acute oral; corncob ... See more keywords

Acute oral colchicine caused gastric mucosal injury and disturbance of associated microbiota in mice.

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recommendations! Published in 2021 at "Toxicology"

DOI: 10.1016/j.tox.2021.152908

Abstract: Colchicine (COL), an ancient and well-known drug, has been used in clinical practice for centuries. On the other hand, COL has also attracted extensive concerns for its potent toxic effects, especially gastrointestinal adverse reactions (nausea,… read more here.

Keywords: associated microbiota; gastric mucosal; acute oral; microbiota mice ... See more keywords
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In Silico Assessment of Acute Oral Toxicity for Mixtures.

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recommendations! Published in 2020 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.0c00256

Abstract: While exposure of humans to environmental hazards often occurs with complex chemical mixtures, the majority of existing toxicity data are for single compounds. The Globally Harmonized System of chemical classification (GHS) developed by the Organization… read more here.

Keywords: ghs category; acute oral; toxicity; toxicity data ... See more keywords

Accurate Prediction of Rat Acute Oral Toxicity and Reference Dose for Thousands of Polycyclic Aromatic Hydrocarbon Derivatives Based on Chemometric QSAR and Machine Learning.

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recommendations! Published in 2024 at "Environmental science & technology"

DOI: 10.1021/acs.est.4c03966

Abstract: Acute oral toxicity is currently not available for most polycyclic aromatic hydrocarbons (PAHs), especially their derivatives, because it is cost-prohibitive to experimentally determine all of them. Here, quantitative structure-activity relationship (QSAR) models using machine learning… read more here.

Keywords: acute oral; oral toxicity; polycyclic aromatic; machine learning ... See more keywords

Synthesis of 2-Monochloropanol Fatty Acid Esters and Their Acute Oral Toxicities in Swiss Mice.

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recommendations! Published in 2019 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.9b01083

Abstract: A novel synthetic route was designed, developed, and utilized to synthesize six high-purity 2-monochloropropanediol fatty acid esters (2-MCPD esters), a group of potential processing-induced food contaminants. A chlorine atom was introduced to C-2 of a… read more here.

Keywords: acid esters; fatty acid; acute oral; oral toxicities ... See more keywords
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Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity

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recommendations! Published in 2021 at "Drug Delivery"

DOI: 10.1080/10717544.2021.1944398

Abstract: Abstract To prepare glutaraldehyde-based cross-linked medium molecular weight chitosan nanoparticles encapsulated with 5-Fluorouracil (5-FU), to overcome dosing frequency as well as reducing acute oral toxicity and poor bioavailability of the drug. Medium molecular weight chitosan… read more here.

Keywords: chitosan nanoparticles; medium molecular; acute oral; drug ... See more keywords

Acute oral and contact toxicity of imidacloprid and thiamethoxam, and their commercial products, to the neotropical stingless bee Melipona scutellaris.

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recommendations! Published in 2025 at "Environmental toxicology and chemistry"

DOI: 10.1093/etojnl/vgaf284

Abstract: Neotropical stingless bees have frequently been reported to possess high biodiversity, ecological significance, and sensitivity to insecticides. Surprisingly, few studies have been conducted so far to assess their sensitivity to neonicotinoid insecticides, although there are… read more here.

Keywords: acute oral; stingless; commercial products; toxicity ... See more keywords

Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies

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recommendations! Published in 2022 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfac042

Abstract: Abstract Regulatory agencies rely upon rodent in vivo acute oral toxicity data to determine hazard categorization, require appropriate precautionary labeling, and perform quantitative risk assessments. As the field of toxicology moves toward animal-free new approach… read more here.

Keywords: toxicity; variability; rat acute; evaluation variability ... See more keywords

Prediction of Acute Oral Systemic Toxicity Using a Multifingerprint Similarity Approach

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recommendations! Published in 2019 at "Toxicological Sciences"

DOI: 10.1093/toxsci/kfy255

Abstract: The implementation of nonanimal approaches is of particular importance to regulatory agencies for the prediction of potential hazards associated with acute exposures to chemicals. This work was carried out in the framework of an international… read more here.

Keywords: oral systemic; similarity; similarity approach; acute oral ... See more keywords

Factors associated with acute oral mucosal reaction induced by radiotherapy in head and neck squamous cell carcinoma

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recommendations! Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000008446

Abstract: Abstract To investigate risk factors for acute oral mucosal reaction during head and neck squamous cell carcinoma radiotherapy. A retrospective study of patients with head and neck squamous cell carcinoma who underwent radiotherapy from November… read more here.

Keywords: mucosal reaction; oral mucosal; acute oral; reaction ... See more keywords