Supramolecular Macrophage‐Liposome Marriage for Cell‐Hitchhiking Delivery and Immunotherapy of Acute Pneumonia and Melanoma
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DOI: 10.1002/adfm.202102440
Abstract: As many diseases are related to inflammation, the inflammatory tropism of immune cells may bring cell‐hitchhikers directly to the disease tissues in a highly targeted manner. The current cell‐hitchhiking strategies rely on either cellular internalization… read more here.
Keywords: cell hitchhiking; acute pneumonia; delivery; macrophage ... See more keywords
Chemotaxis‐guided Self‐propelled Macrophage Motor for Targeted Treatment of Acute Pneumonia
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DOI: 10.1002/adma.202211626
Abstract: Immune cells exhibit great potential as carriers of nanomedicine, attributed to their high tolerance to internalized nanomaterials and targeted accumulation in inflammatory tissues. However, the premature efflux of internalized nanomedicine during systemic delivery and slow… read more here.
Keywords: chemotaxis guided; acute pneumonia; treatment acute;
Assessment of polymyxin B - doxycycline combination against Pseudomonas aeruginosa in in vitro and in a mouse acute pneumonia model.
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DOI: 10.1016/j.ijantimicag.2020.106022
Abstract: The increasing prevalence of antibiotic resistance in Pseudomonas aeruginosa has created an urgent need for suitable therapy. Here we systematically explored the pairing of doxycycline with other antipseudomonal antibiotic partners and found a synergistic combination… read more here.
Keywords: combination; acute pneumonia; pneumonia model; polymyxin doxycycline ... See more keywords
Targeted delivery of dexamethasone in acute pneumonia.
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DOI: 10.1039/d1bm00924a
Abstract: Pneumonia has contributed to significant mortality owing to the irreversible injury to the lungs and severe inflammation of the tissue. Dexamethasone (DEX) is regarded as an effective drug to relieve the level of pneumonia, while… read more here.
Keywords: dexamethasone; acute pneumonia; targeted delivery; pneumonia ... See more keywords
Ganoderma lucidum polysaccharides ameliorate lipopolysaccharide-induced acute pneumonia via inhibiting NRP1-mediated inflammation
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DOI: 10.1080/13880209.2022.2142615
Abstract: Abstract Context Ganoderma lucidum polysaccharides (GLP), from Ganoderma lucidum (Leyss. ex Fr.) Karst. (Ganodermataceae), are reported to have anti-inflammatory effects, including anti-neuroinflammation and anti-colitis. Nevertheless, the role of GLP in acute pneumonia is unknown. Objective… read more here.
Keywords: pneumonia; induced acute; ganoderma lucidum; lucidum polysaccharides ... See more keywords