Complications and early mortality in patients with acute promyelocytic leukemia treated in California
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25252
Abstract: globulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients. Leukemia. 2018. https://doi.org/10.1038/ s41375-018-0194-x 3. Kohlhagen MC, Barnidge DR, Mills JR, et al. Screening method for M-proteins in serum… read more here.
Keywords: acute promyelocytic; early mortality; patients acute; promyelocytic leukemia ... See more keywords
Recapturing disease response: A phase 2 study of carfilzomib 56 mg/m2 in patients with relapsed or refractory multiple myeloma who have progressed on carfilzomib 27 mg/m2
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25695
Abstract: 1. Lo-Coco F, Avvisati G, Vignetti M, et al. Retinoic acid and arsenic trioxide for acute promyelocytic leukemia. N Engl J Med. 2013;369: 111-121. 2. Nagendra S, Meyerson H, Skallerud G, et al. Leukemias resembling… read more here.
Keywords: acute promyelocytic; myeloid leukemia; promyelocytic leukemia; acute myeloid ... See more keywords
Impact of insurance status on the survival of younger patients diagnosed with acute promyelocytic leukemia in the United States
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DOI: 10.1002/cncr.33593
Abstract: Survival among patients diagnosed with acute promyelocytic leukemia (APL) has significantly improved with the use of all‐trans retinoic acid and arsenic trioxide. However, the need for immediate diagnosis and access to specialized care and the… read more here.
Keywords: acute promyelocytic; promyelocytic leukemia; diagnosed acute; patients diagnosed ... See more keywords
Successful treatment of acute promyelocytic leukemia in pregnancy with single-agent all-trans retinoic acid
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DOI: 10.1007/s00404-017-4583-6
Abstract: PurposeThe diagnosis of acute promyelocytic leukemia (APL) in pregnancy is an uncommon, life-threatening emergency. Choice of treatment and management of complications are challenging.MethodsWe report the case of a patient with diagnosis of APL at gestational… read more here.
Keywords: agent; pregnancy; acute promyelocytic; apl pregnancy ... See more keywords
Cell dynamics during differentiation therapy with all-trans retinoic acid in acute promyelocytic leukemia
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2472-9
Abstract: The introduction of all-trans retinoic acid (ATRA) has made acute promyelocytic leukemia (APL) a curable disease; however, early death prior to the completion of treatment remains a problem. In quantitative evaluation of response to ATRA… read more here.
Keywords: trans retinoic; acute promyelocytic; promyelocytic leukemia; differentiation ... See more keywords
The global problem of early deaths in acute promyelocytic leukemia: A strategy to decrease induction mortality in the most curable leukemia.
Sign Up to like & getrecommendations! Published in 2018 at "Blood reviews"
DOI: 10.1016/j.blre.2017.09.001
Abstract: Acute promyelocytic leukemia (APL) is a hyper-acute illness and presents with profound cytopenias in most patients and disseminated intravascular coagulation (DIC). Excellent treatment options are now available with drugs such as all-trans retinoic acid (ATRA),… read more here.
Keywords: early deaths; acute promyelocytic; promyelocytic leukemia; global problem ... See more keywords
Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2019.06.007
Abstract: The detection of PML/RARA or variant RARA rearrangements is critical for the diagnosis and treatment of patients with newly diagnosed acute promyelocytic leukemia (APL). While most cases of APL harboring the PML/RARA fusion respond to… read more here.
Keywords: acute promyelocytic; fusion; diagnosed acute; rara ... See more keywords
Effect of daunorubicin on acute promyelocytic leukemia cells using nuclear magnetic resonance spectroscopy-based metabolomics.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2020.103382
Abstract: The aim of this study was to determine several key metabolites as potential biomarkers of daunorubicin (DNR) treatment of acute promyelocytic leukemia (APL) using APL blasts and NB4 cells. Samples which were obtained from 16… read more here.
Keywords: nuclear magnetic; acute promyelocytic; promyelocytic leukemia; magnetic resonance ... See more keywords
No prognostic significance of normalized copy number of PML-RARA transcript at diagnosis in patients with acute promyelocytic leukemia.
Sign Up to like & getrecommendations! Published in 2020 at "Hematology/oncology and stem cell therapy"
DOI: 10.1016/j.hemonc.2020.07.002
Abstract: BACKGROUND Acute promyelocytic leukemia is a peculiar disease with few studies that have investigated the prognostic significance of PML/RARA transcript level at diagnosis. PATIENTS AND METHODS This retrospective study included all cases diagnosed with acute… read more here.
Keywords: pml rara; promyelocytic leukemia; acute promyelocytic; diagnosis ... See more keywords
Treatment of acute promyelocytic leukemia in older patients: recommendations of an International Society of Geriatric Oncology (SIOG) task force.
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DOI: 10.1016/j.jgo.2020.03.019
Abstract: Approximately one third of patients diagnosed with acute promyelocytic leukemia (APL) are above the age of sixty. It is important to ensure older adults receive optimal diagnosis and management since this subtype of acute myeloid… read more here.
Keywords: acute promyelocytic; promyelocytic leukemia; oncology; geriatric oncology ... See more keywords
Acute promyelocytic leukemia presenting with features of metastatic osseous disease
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DOI: 10.1016/j.lrr.2018.02.003
Abstract: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia defined by a balanced translocation between chromosomes 15 and 17 resulting in fusion of the promyelocytic leukemia gene (PML) on chromosome 15 with… read more here.
Keywords: osseous disease; metastatic osseous; acute promyelocytic; promyelocytic leukemia ... See more keywords