Acute spinal cord injury is associated with mitochondrial dysfunction in mouse urothelium
Sign Up to like & getrecommendations! Published in 2019 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24037
Abstract: To characterize the effects of acute spinal cord injury (SCI) on mitochondrial morphology and function in bladder urothelium and to test the therapeutic efficacy of early treatment with the mitochondrially targeted antioxidant, MitoTempo. read more here.
Keywords: injury associated; cord injury; acute spinal; spinal cord ... See more keywords
Natural Polyphenol Delivered Methylprednisolone Achieve Targeted Enrichment for Acute Spinal Cord Injury Therapy.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202404815
Abstract: The strong anti-inflammatory effect of methylprednisolone (MP) is a necessary treatment for various severe cases including acute spinal cord injury (SCI). However, concerns have been raised regarding adverse effects from MP, which also severely limits… read more here.
Keywords: acute spinal; treatment; spinal cord; targeted enrichment ... See more keywords
Anesthesia for Acute Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2021 at "Anesthesiology clinics"
DOI: 10.1016/j.anclin.2020.11.011
Abstract: The spinal cord extends from the base of the skull to the first lumbar vertebrae from which it continues as cauda equina. Injuries to the spinal cord can lead to significant short- and long-term morbidities.… read more here.
Keywords: acute spinal; cord; anesthesia acute; cord injury ... See more keywords
Treatment of Acute Spinal Cord Injuries: A Survey Among Iberolatinoamerican Spine Surgeons – Part 2 Timing to Surgery
Sign Up to like & getrecommendations! Published in 2022 at "Revista Brasileira de Ortopedia"
DOI: 10.1055/s-0042-1746181
Abstract: Objective The objective of the present study was to evaluate the current practice in terms of timing to surgery in acute spinal cord injury (ASCI) patients among spinal surgeons from Iberolatinoamerican countries. Methods A descriptive… read more here.
Keywords: cord; timing surgery; surgery; acute spinal ... See more keywords
Treatment of Acute Spinal Cord Injuries: A Survey Among Iberolatinoamerican Spine Surgeons – Part 1: Use of High-Dose Corticosteroids
Sign Up to like & getrecommendations! Published in 2022 at "Revista Brasileira de Ortopedia"
DOI: 10.1055/s-0042-1749414
Abstract: Objective The aim of the present study was to evaluate the current practice of using of methylprednisolone sodium succinate (MPSS) in acute spinal cord Injuries (ASCIs) among spine surgeons from Iberolatinoamerican countries. Methods A descriptive… read more here.
Keywords: cord injuries; spine surgeons; acute spinal; survey ... See more keywords
“Owl's eyes” sign in acute spinal cord infarction in newborn submitted to aortoplasty
Sign Up to like & getrecommendations! Published in 2022 at "Arquivos de Neuro-Psiquiatria"
DOI: 10.1055/s-0042-1758392
Abstract: A 12-day-old male patient underwent aortoplasty for aortic arch coarctation with patent ductus arteriosus and ventric-ular septal defect. On the 5 th postoperative day, he presented with acute hypore fl exia, tetraparesis, and urinary retention.… read more here.
Keywords: cord; eyes sign; cord infarction; acute spinal ... See more keywords
Trends in the Use of Corticosteroids in the Management of Acute Spinal Cord Injury in North American Clinical Trials Networks (NACTN) Sites.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurotrauma"
DOI: 10.1089/neu.2022.0409
Abstract: Immunomodulatory therapeutics represent a potential neuroprotective strategy for the management of acute spinal cord injury (SCI). One of the most intensely debated neuroprotective drugs has been methylprednisolone sodium succinate (MPSS). MPSS was initially investigated for… read more here.
Keywords: practice; acute sci; acute spinal; management ... See more keywords
Prehospital Cardiovascular Autoregulatory Disturbances Correlate With the Functional Neuroanatomy of Acute Spinal Cord Injury
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DOI: 10.1097/brs.0000000000004571
Abstract: Study Design. Retrospective study. Objective. The importance of attenuating the cardiovascular autoregulatory disturbances accompanying acute spinal cord injury (SCI) has long been recognized. This report assembles SCI emergency service data and correlates cardiovascular parameters to… read more here.
Keywords: autoregulatory disturbances; acute spinal; injury; cardiovascular autoregulatory ... See more keywords
An Analysis of Medical Malpractice Litigation due to Intravenous Steroid Treatment for Acute Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Spine"
DOI: 10.1097/brs.0000000000004708
Abstract: STUDY DESIGN Retrospective cohort study. OBJECTIVE To evaluate the incidence of litigation due to using or foregoing methylprednisolone, naloxone, or tirilazad for treatment of acute spinal cord injury (ASCI) through querying the Westlaw and VerdictSearch… read more here.
Keywords: litigation due; acute spinal; litigation; treatment ... See more keywords
Protocol for the Chinese Real-World Evidence for Acute Spinal Cord Injury (ChiRES) study: a prospective, observational, multicentre cohort study of acute spinal cord injury
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DOI: 10.1136/bmjopen-2023-080358
Abstract: Introduction Spinal cord injury (SCI) is a catastrophic event with devastating physical, social and occupational consequences for patients and their families. The number of patients with acute SCI in China continues to grow rapidly, but… read more here.
Keywords: acute spinal; acute sci; spinal cord; cord injury ... See more keywords
Highlight article: Identification of serum exosomal microRNAs in acute spinal cord injured rats
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370219872759
Abstract: It is important to find specific and easily detectable diagnostic markers in acute stage of spinal cord injury for guiding treatment and estimating prognosis. Although, microRNAs are attractive biomarkers, there is still no uniform standard… read more here.
Keywords: acute spinal; cord; serum exosomal; cord injury ... See more keywords