Borane-Catalyzed Direct Asymmetric Vinylogous Mannich Reactions of Acyclic α,β-Unsaturated Ketones.
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DOI: 10.1021/jacs.1c00006
Abstract: Herein, we report that, by using chiral bicyclic bisborane catalysts, we have achieved the first highly regio-, diastereo-, and enantioselective direct asymmetric vinylogous Mannich reactions of acyclic α,β-unsaturated ketones. The strong Lewis acidity and steric… read more here.
Keywords: acyclic unsaturated; direct asymmetric; asymmetric vinylogous; reactions acyclic ... See more keywords