An 8-(Diazomethyl) Quinoline Derivatized Acyl-CoA in Silico Mass Spectral Library Reveals the Landscape of Acyl-CoA in Aging Mouse Organs.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c02113
Abstract: Acyl-Coenzyme As (acyl-CoAs) are essential intermediates to incorporate carboxylic acids into the bioactive metabolic network across all species, which play important roles in lipid remodeling, fatty acids, and xenobiotic carboxylic metabolism. However, due to the… read more here.
Keywords: coa; library; acyl coas; acyl coa ... See more keywords
Quantitative analysis of protein lipidation and acyl-CoAs reveals substrate preferences of the S-acylation machinery
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DOI: 10.1039/d4sc02235a
Abstract: Protein palmitoylation or S-acylation has emerged as a key regulator of cellular processes. Increasing evidence shows that this modification is not restricted to palmitate but it can include additional fatty acids, raising the possibility that… read more here.
Keywords: protein; acyl coas; quantitative analysis; acylation ... See more keywords
Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria
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DOI: 10.1098/rsob.170087
Abstract: One of the dominant features of the biology of Mycobacterium tuberculosis, and other mycobacteria, is the mycobacterial cell envelope with its exceptional complex composition. Mycolic acids are major and very specific components of the cell… read more here.
Keywords: biosynthesis; mycolic acid; mabr; acyl coas ... See more keywords
A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs
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DOI: 10.3390/metabo11080468
Abstract: Coenzyme A (CoA) is an essential cofactor for dozens of reactions in intermediary metabolism. Dysregulation of CoA synthesis or acyl CoA metabolism can result in metabolic or neurodegenerative disease. Although several methods use liquid chromatography… read more here.
Keywords: acyl coas; coa biosynthetic; short chain; coa ... See more keywords