Visible-Light-Driven Hydroacylation of Unactivated Alkenes Using Readily Available Acyl Donors.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04337
Abstract: Herein, we report visible-light-driven hydroacylation of unactivated alkenes. We employed benzimidazolines as new acyl donors and achieved perfect regioselectivity, high functional-group tolerance, and excellent substrate generality. We also performed mechanistic experiments to elucidate the detailed… read more here.
Keywords: hydroacylation unactivated; light driven; visible light; acyl donors ... See more keywords
Structural Basis of Specificity for Carboxyl-terminated Acyl Donors in A Bacterial Acyltransferase.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c07331
Abstract: Macrolactins (MLNs) are a class of important antimacular degeneration and antitumor agents. Malonylated/succinylated MLNs are even more important due to their efficacy to overcome multidrug resistant bacteria. However, which enzyme catalyzes this reaction remains enigmatic.… read more here.
Keywords: bmmi; geometry; terminated acyl; carboxyl terminated ... See more keywords