Metal-Free Synthesis of Acyl Glycosides and Application to Oligosaccharide Synthesis.
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DOI: 10.1021/acs.orglett.2c03661
Abstract: Oligosaccharides are involved in numerous biological processes. Achieving optimal anomeric selectivity and regioselectivity remains challenging. Herein, we present a method for the oxidative glycosylation of thioglycosides with hypervalent iodine reagents derived from carboxylic acid to… read more here.
Keywords: glycosides application; acyl glycosides; synthesis acyl; metal free ... See more keywords
β-Selective One-Pot Synthesis of Acyl-C-Glycosides via Corey–Seebach Umpolung Reaction
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DOI: 10.1055/s-0039-1690158
Abstract: C-Glycosides are commonly used as carbohydrate mimics in drug development due to their stability against enzymatic and chemical hydrolysis. In this Synpacts article we elaborate on our fast and efficient β-selective approach towards protected and… read more here.
Keywords: umpolung reaction; corey seebach; acyl; acyl glycosides ... See more keywords