Human Fatty Acid Synthase: A Computational Study of the Transfer of the Acyl Moieties from MAT to the ACP Domain
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DOI: 10.1002/cctc.201900548
Abstract: Human Fatty Acid Synthase (hFAS) is a multidomain enzyme responsible for the biosynthesis of saturated fatty acids, which are crucial for numerous biological processes. During the biosynthetic reaction, hFAS incorporates acetyl and malonyl moieties through… read more here.
Keywords: human fatty; fatty acid; acyl; acp domain ... See more keywords
Ribosomally derived lipopeptides containing distinct fatty acyl moieties
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2113120119
Abstract: Significance Fatty-acylated lipopeptides are metabolites of high medical and biotechnological importance, exemplified by the clinically used daptomycin, polymyxin, and echinocandin anti-infectives. The known representatives are produced by giant nonribosomal enzymes that usually generate heterogeneously acylated… read more here.
Keywords: fatty acylated; distinct fatty; acyl moieties; fatty acyl ... See more keywords
Accumulation of medium-chain, saturated fatty acyl moieties in seed oils of transgenic Camelina sativa
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DOI: 10.1371/journal.pone.0172296
Abstract: With its high seed oil content, the mustard family plant Camelina sativa has gained attention as a potential biofuel source. As a bioenergy crop, camelina has many advantages. It grows on marginal land with low… read more here.
Keywords: chain; seed; camelina; seed oils ... See more keywords