Articles with "acyl thiophene" as a keyword



Electrochemical Dearomative Spirocyclization of N-Acyl Thiophene-2-sulfonamides.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c02536

Abstract: The Friedel-Crafts type alkylation of C2-tethered thiophenes has been reported to be nonregioselective. Taking advantage of the highly regioselective 5-exo-trig spirocyclization of an electrochemically generated amidyl radical, we have unraveled an electrochemical dearomative spirocyclization of… read more here.

Keywords: spirocyclization; dearomative spirocyclization; acyl thiophene; thiophene sulfonamides ... See more keywords