Recent topics in enantioselective acyl transfer reactions with dialkylaminopyridine-based nucleophilic catalysts
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.03.016
Abstract: Abstract This digest focuses on recent topics in intra- and intermolecular enantioselective acyl transfer reactions with dialkylaminopyridine-based catalysts over the past decade (2007–2017). The structures of the catalysts are divided into four categories according to… read more here.
Keywords: acyl transfer; transfer reactions; recent topics; enantioselective acyl ... See more keywords
α-Nitro-α,β-Unsaturated Ketones: An Electrophilic Acyl Transfer Reagent in Catalytic Asymmetric Friedel-Crafts and Michael Reactions.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02310
Abstract: Herein, we introduce α-nitro-α,β-unsaturated ketones as efficient electrophilic acyl transfer reagents, and they were employed in Friedel-Crafts as well as in Michael reactions. The desired acyl transfer products of these reactions were obtained in high… read more here.
Keywords: electrophilic acyl; acyl transfer; unsaturated ketones; michael reactions ... See more keywords
Enzyme-like Acyl Transfer Catalysis in a Bifunctional Organic Cage
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c03560
Abstract: Amide-based organic cage cavities are, in principle, ideal enzyme active site mimics. Yet, cage-promoted organocatalysis has remained elusive, in large part due to synthetic accessibility of robust and functional scaffolds. Herein, we report the acyl… read more here.
Keywords: transfer catalysis; acyl; organic cage; cage ... See more keywords
Regio- and diastereoselective construction of conjugate oxindole derivatives enabled by delayed acyl transfer of pyridinium ylides
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00412k
Abstract: Herein, we design and develop a one-pot cascade strategy for the assembly of multi-substituted conjugate oxindole derivatives. This approach represents a new reaction mode for carbene gem-difunctionalization by delayed acyl transfer instead of delayed proton… read more here.
Keywords: transfer; oxindole derivatives; conjugate oxindole; acyl transfer ... See more keywords
Synthesis of chiral β-hydroxy allylic sulfides via iridium-catalyzed asymmetric cascade allylation/acyl transfer rearrangement.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical communications"
DOI: 10.1039/d5cc00422e
Abstract: Iridium-catalyzed asymmetric allylation/acyl transfer rearrangement of thioesters and vinyl ethylene carbonate (VEC) has been developed. A wide range of structurally important chiral β-hydroxy allylic sulfide derivatives could be prepared in good yields with excellent enantioselectivity. read more here.
Keywords: iridium catalyzed; transfer rearrangement; acyl transfer; allylation acyl ... See more keywords
Acyl Transfer Strategies as Transient Activations for Enantioselective Synthesis
Sign Up to like & getrecommendations! Published in 2019 at "Synthesis"
DOI: 10.1055/s-0037-1611743
Abstract: In order to circumvent reactivity or selectivity issues associated with the addition of enolates to electrophiles, chemists have devised innovative methods involving transient activating groups. One of these powerful methods consists of the use of… read more here.
Keywords: transfer strategies; acyl transfer; transfer; synthesis acyl ... See more keywords