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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28052319
Abstract: In search of synthetically accessible open-ring analogs of PD144418 or 5-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl)-3-(p-tolyl)isoxazole, a highly potent sigma-1 receptor (σ1R) ligand, we herein report the design and synthesis of sixteen arylated acyl urea derivatives. Design aspects included modeling…
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Keywords:
design synthesis;
new acyl;
urea analogs;
synthesis new ... See more keywords