Synthesis of novel 4′-acylamino modified 21E-benzylidene steroidal derivatives and their cytotoxic activities
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DOI: 10.1016/j.steroids.2017.04.006
Abstract: &NA; A series of 4′‐acylamino modified &Dgr;1,4‐pregnadien‐21E‐benzylidene‐3,20‐dione derivatives (6a–v) was synthesized from the commercially available progesterone (1). These title compounds were evaluated for their toxicity against brine shrimp (Artemia salina) and cytotoxic activities against two… read more here.
Keywords: cytotoxic activities; 21e benzylidene; acylamino modified; modified 21e ... See more keywords