Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.
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DOI: 10.1016/j.celrep.2021.109460
Abstract: In addition to acetylation, histones are modified by a series of competing longer-chain acylations. Most of these acylation marks are enriched and co-exist with acetylation on active gene regulatory elements. Their seemingly redundant functions hinder… read more here.
Keywords: h4k5; acetylation; acylation; ratio ... See more keywords