New Conformations of Acylation Adducts of Inhibitors of beta-Lactamase from Mycobacterium tuberculosis.
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DOI: 10.2210/pdb6h2a/pdb
Abstract: Mycobacterium tuberculosis (Mtb), the main causative agent of tuberculosis (TB), is naturally resistant to β-lactam antibiotics due to the production of the extended spectrum β-lactamase BlaC. β-Lactam/β-lactamase inhibitor combination therapies can circumvent the BlaC-mediated resistance… read more here.
Keywords: mycobacterium tuberculosis; blac; lactamase; tuberculosis ... See more keywords