Transannular Acylation Facilitates C5–C9 Bond Formation in Hyperforin Total Synthesis
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DOI: 10.1021/acs.orglett.5c00243
Abstract: Hyperforin is considered the flagship congener among polycyclic polyprenylated acylphloroglucinols due to its compelling and complex molecular architecture, coupled with remarkable biological activity, thus rendering it an appealing synthetic target for chemists over the past… read more here.
Keywords: hyperforin; total synthesis; transannular acylation; acylation facilitates ... See more keywords