Palladium-catalyzed intramolecular C H acylation of indoles with thioester
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DOI: 10.1016/j.tetlet.2019.151061
Abstract: Abstract A palladium-catalyzed intramolecular C H acylation of indole with thioester is described, providing a direct and effective approach for the synthesis of the biologically active indole-indolone scaffolds. The method obviates the need for the… read more here.
Keywords: intramolecular acylation; acylation indoles; indoles thioester; palladium catalyzed ... See more keywords
Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
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DOI: 10.3390/molecules27238281
Abstract: An efficient, high-yielding and scalable procedure for the regioselective 3-acylation of indoles with anhydrides promoted by boron trifluoride etherate under mild conditions was reported. This novel protocol provided a simple way to prepare 3-(benzofuran-2-yl) indole… read more here.
Keywords: boron trifluoride; regioselective acylation; trifluoride etherate; acylation indoles ... See more keywords
Chemoselective N-acylation of indoles using thioesters as acyl source
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.18.9
Abstract: The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source.… read more here.
Keywords: using thioesters; acyl source; indoles using; acylation indoles ... See more keywords