Microwave-assisted synthesis, characterization and bioassay of acylhydrazone derivatives as influenza neuraminidase inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-2015-6
Abstract: A series of acylhydrazone derivatives (4a–4s) were synthesized via microwave irradiation with short reaction time and good yields. The crystal structure of compound 4j was further determined by single-crystal X-ray diffraction. All of the derivatives… read more here.
Keywords: microwave assisted; assisted synthesis; neuraminidase inhibitors; influenza neuraminidase ... See more keywords
Crystal structures of three ortho-substituted N-acylhydrazone derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989017016814
Abstract: The effect of the nature of substitutions on the structural parameters and hydrogen-bonding interactions in N-acylhydrazone derivatives has been studied by synthesizing and determining the crystal structures of three ortho-substituted N-acylhydrazone derivatives, namely (E)-N-{2-[2-(2-chlorobenzylidene)hydrazinyl]-2-oxoethyl}-4-methylbenzenesulfonamide (I),… read more here.
Keywords: substituted acylhydrazone; ortho substituted; crystal structures; acylhydrazone derivatives ... See more keywords
Novel Regioisomeric Analogues of Naphthyl-N-Acylhydrazone Derivatives and Their Anti-Inflammatory Effects
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113562
Abstract: Background: When homeostasis is disturbed it can result in a pathological event named inflammation. The main drugs used in the treatment consist of non-steroidal and steroidal anti-inflammatory drugs. However, the side effects remain an obstacle… read more here.
Keywords: lassbio 2039; acylhydrazone derivatives; anti inflammatory; naphthyl acylhydrazone ... See more keywords