Adenoviral Vector Delivery of vegf, Angiogenin, and gdnf Genes Promotes Angiogenesis in Ischemic Skeletal Muscle
Sign Up to like & getrecommendations! Published in 2020 at "BioNanoScience"
DOI: 10.1007/s12668-019-00688-y
Abstract: Effects of adenoviruses carrying genes of a vascular endothelial growth factor ( vegf 165 ), a glial-cell derived neurotrophic factor ( gdnf ), and angiogenin ( ang ) were studied in a rat model of… read more here.
Keywords: ad5 ang; vegf; ad5; gdnf ... See more keywords
Chitosan Modification-Enhanced Silencing Effect of Ad5-shPDGF-D Vector in Breast Cancer Cell Line MDA-MB-231.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug delivery"
DOI: 10.2174/1567201819666220429093821
Abstract: BACKGROUND Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because it is known to play roles in… read more here.
Keywords: breast; ad5; vector; cell line ... See more keywords
In Vivo Tracking for Oncolytic Adenovirus Interactions with Liver Cells
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071697
Abstract: Hepatotoxicity remains an as yet unsolved problem for adenovirus (Ad) cancer therapy. The toxic effects originate both from rapid Kupffer cell (KCs) death (early phase) and hepatocyte transduction (late phase). Several host factors and capsid… read more here.
Keywords: vivo tracking; ad5; liver cells; hepatotoxicity ... See more keywords