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   Articles with "ad5" as a keyword



Adenoviral Vector Delivery of vegf, Angiogenin, and gdnf Genes Promotes Angiogenesis in Ischemic Skeletal Muscle

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recommendations! Published in 2020 at "BioNanoScience"

DOI: 10.1007/s12668-019-00688-y

Abstract: Effects of adenoviruses carrying genes of a vascular endothelial growth factor ( vegf 165 ), a glial-cell derived neurotrophic factor ( gdnf ), and angiogenin ( ang ) were studied in a rat model of… read more here.

Keywords: ad5 ang; vegf; ad5; gdnf ... See more keywords

Chitosan Modification-Enhanced Silencing Effect of Ad5-shPDGF-D Vector in Breast Cancer Cell Line MDA-MB-231.

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recommendations! Published in 2022 at "Current drug delivery"

DOI: 10.2174/1567201819666220429093821

Abstract: BACKGROUND Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because it is known to play roles in… read more here.

Keywords: breast; ad5; vector; cell line ... See more keywords

In Vivo Tracking for Oncolytic Adenovirus Interactions with Liver Cells

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recommendations! Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10071697

Abstract: Hepatotoxicity remains an as yet unsolved problem for adenovirus (Ad) cancer therapy. The toxic effects originate both from rapid Kupffer cell (KCs) death (early phase) and hepatocyte transduction (late phase). Several host factors and capsid… read more here.

Keywords: vivo tracking; ad5; liver cells; hepatotoxicity ... See more keywords

Adenovirus-Neutralizing and Infection-Promoting Activities Measured in Serum of Human Brain Cancer Patients Treated with Oncolytic Adenovirus Ad5-∆24.RGD

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recommendations! Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26020854

Abstract: Oncolytic adenoviruses derived from human serotype 5 (Ad5) are being developed to treat cancer. Treatment efficacy could be affected by pre-existing or induced neutralizing antibodies (NAbs), in particular in repeat administration strategies. Several oncolytic adenoviruses… read more here.

Keywords: cancer; ad5 rgd; ad5; rgd ... See more keywords