The Effects of Storage Conditions and Homogenisation Buffers on the Measurement of SOD, CAT and ADA Enzyme Activities in Cattle Liver
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.70418
Abstract: ABSTRACT Background Accurate measurement of enzyme activities is very important in studies to evaluate enzymatic parameters. While performing these measurements, many factors can affect the results, including the method of obtaining the tissues, the conditions… read more here.
Keywords: cat; ada; homogenisation buffers; enzyme activities ... See more keywords
Multi-Year Registry Study of Elapegademase Treatment in Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) Requiring Enzyme Replacement Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-025-01873-3
Abstract: The safety and tolerability of elapegademase (elapegademase-lvlr; Revcovi®) a PEGylated recombinant adenosine deaminase (ADA), were demonstrated in two Phase 3 clinical trials in the U.S. and Japan in patients with ADA-deficient severe combined immunodeficiency (ADA-SCID).… read more here.
Keywords: adenosine deaminase; ada; elapegademase; severe combined ... See more keywords
Citrullination of adenosine deaminase impairs its binding to dipeptidyl peptidase IV.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2022.106820
Abstract: The presence of citrullinated adenosine deaminase (ADA) was reported in the synovial fluids of rheumatoid arthritis individuals. This work reports the effects of ADA citrullination on the formation/stabilization of ADA complex with dipeptidyl peptidase IV… read more here.
Keywords: dipeptidyl peptidase; ada; citrullination; adenosine deaminase ... See more keywords
Diagnostic accuracy of ADA 2020 criteria for undiagnosed diabetes in a Peruvian population.
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2020.108475
Abstract: AIMS To assess the prevalence of undiagnosed diabetes (UDD) and the diagnostic accuracy of the American Diabetes Association (ADA) criteria to detect UDD cases in a Peruvian population. METHODS Population-based cross-sectional study. UDD was defined… read more here.
Keywords: ada; accuracy; diagnostic accuracy; undiagnosed diabetes ... See more keywords
Scaffold for liver tissue engineering: Exploring the potential of fibrin incorporated alginate dialdehyde-gelatin hydrogel.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.10.256
Abstract: INTRODUCTION Development of a tissue-engineered construct for hepatic regeneration remains a challenging task due to the lack of an optimum environment that support the growth of hepatocytes. Hydrogel systems possess many similarities with tissues and… read more here.
Keywords: liver tissue; hydrogel; ada; tissue ... See more keywords
Aflatoxins produced by Aspergillus parasiticus present in the diet of quails increase the activities of cholinesterase and adenosine deaminase.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.03.041
Abstract: The aim of this study was to evaluate the effects of aflatoxins on cholinesterases (acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and adenosine deaminase (ADA) activities in quails. For this, twenty male quails were randomly distributed into… read more here.
Keywords: ache; ada; group; adenosine deaminase ... See more keywords
Intensive and Persistent Chemiluminescence from Orderly Arranged Ligands within Metal-Organic Frameworks for Inflammation Imaging.
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c05171
Abstract: Chemiluminescence offers ultrasensitive imaging for the diagnosis of a variety of diseases by removing the interference from excitation light sources. Here, we prepared two chemiluminescent metal-organic frameworks (Mn-ADA and Zn-ADA) by using (2E,2'E)-3,3'-(anthracene-9,10-diyl)diacrylic acid (ADA)… read more here.
Keywords: persistent chemiluminescence; ada; organic frameworks; chemiluminescence ... See more keywords
Targeting adenosine in SSc
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-020-0435-z
Abstract: Aberrant activation of adenosinedependent signalling has been implicated in a number of fibrotic diseases, including systemic sclerosis (SSc). The results of a new study indicate that adenosine depletion with recombinant pegylated adenosine deaminase (PEG-ADA) improves… read more here.
Keywords: ssc; ada; treatment; fra2 transgenic ... See more keywords
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40136
Abstract: Adenosine Deaminase (ADA) deficiency is an autosomal recessive variant of severe combined immunodeficiency (SCID) caused by systemic accumulation of ADA substrates. Neurological and behavioral abnormalities observed in ADA-SCID patients surviving after stem cell transplantation or… read more here.
Keywords: alterations brain; ada; brain adenosine; deficient mice ... See more keywords
Random acceleration and steered molecular dynamics simulations reveal the (un)binding tunnels in adenosine deaminase and critical residues in tunnels
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra07796h
Abstract: Adenosine deaminase (ADA) is an important enzyme related to purine nucleoside metabolism in human serum and various tissues. Abnormal ADA levels are related to a wide variety of diseases such as rheumatoid arthritis, AIDS, anemia,… read more here.
Keywords: molecular dynamics; ada; steered molecular; adenosine deaminase ... See more keywords
Adalimumab Dose Reduction and Withdrawal in Stable Non-Infectious Pediatric Uveitis: An Open-Label, Prospective, Pilot Study
Sign Up to like & getrecommendations! Published in 2024 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2024.2343084
Abstract: ABSTRACT Purposes This study investigated the feasibility of adalimumab (ADA) dose reduction and withdrawal strategy in children with stable pediatric non-infectious uveitis (PNIU). Methods This open-label prospective pilot trial recruited 18 stable PNIU patients (33… read more here.
Keywords: dose reduction; uveitis; ada; reduction withdrawal ... See more keywords