Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients
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DOI: 10.1038/srep40136
Abstract: Adenosine Deaminase (ADA) deficiency is an autosomal recessive variant of severe combined immunodeficiency (SCID) caused by systemic accumulation of ADA substrates. Neurological and behavioral abnormalities observed in ADA-SCID patients surviving after stem cell transplantation or… read more here.
Keywords: alterations brain; ada; brain adenosine; deficient mice ... See more keywords