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ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis

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0 Published in 2017 at "Nature medicine"

DOI: 10.1038/nm.4419

Abstract: Maladaptive wound healing responses to chronic tissue injury result in organ fibrosis. Fibrosis, which entails excessive extracellular matrix (ECM) deposition and tissue remodeling by activated myofibroblasts, leads to loss of proper tissue architecture and organ… read more here.

Keywords: fibrosis; myofibroblast activation; activation; adam10 mediated ... See more keywords