Articles with "adam15" as a keyword



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Abstract LB-B08: Validation of ADAM15 as a therapeutic target in invasive bladder cancer cells

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Published in 2018 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-17-lb-b08

Abstract: Introduction: Advanced bladder cancer is a deadly and costly disease with locally invasive tumors carrying the worst prognosis for progression and mortality. The ADAM15 membrane disintegrin is key regulator in the invasive processes. Our previous… read more here.

Keywords: bladder cancer; invasive bladder; adam15; cancer cells ... See more keywords
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Abstract 306: Loss of a Disintegrin and Metalloproteinase-15 Impairs Fibroblast Activation Following Myocardial Infarction Resulting in Ventricular Rupture

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Published in 2020 at "Circulation Research"

DOI: 10.1161/res.127.suppl_1.306

Abstract: Background: Myocardial infarction (MI) occurs when blood flow to a region of the myocardium is interrupted. Over time, the damaged myocardium is replaced with scar tissue through activation of an inflammatory phase, followed by a… read more here.

Keywords: adam15; rupture; myocardial infarction; disintegrin metalloproteinase ... See more keywords