Synthesis and biological evaluation of 1-(2-(adamantane-1-yl)-1H-indol-5-yl)-3-substituted urea/thiourea derivatives as anticancer agents
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DOI: 10.1039/c7ra08149a
Abstract: The indole ring, adamantane, and urea groups are important components of bioactive molecules. The orphan nuclear receptor Nur77 as a unique transcription factor encoded by an immediate early gene is a potential therapeutic target for… read more here.
Keywords: substituted urea; thiourea derivatives; adamantane indol; cancer ... See more keywords