Adamantylation of N-aryl and N-arylalkyl acetamides in trifluoroacetic acid
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DOI: 10.1007/s11172-020-2873-9
Abstract: Alkylation of N-aryl and N-arylalkyl acetamides with hydroxy adamantane derivatives in trifluoroacetic acid was studied. The differentiating effect of trifluoroacetic acid on the regio-selectivity of adamantylation of o-alkyl-substituted acetanilides was established, leading to energetically more… read more here.
Keywords: trifluoroacetic acid; aryl arylalkyl; adamantylation aryl; acetamides trifluoroacetic ... See more keywords