Articles with "adamgammadex" as a keyword



Efficacy and safety of adamgammadex for reversing rocuronium‐induced deep neuromuscular blockade: A multicenter, randomized, phase IIb study

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Published in 2024 at "Clinical and Translational Science"

DOI: 10.1111/cts.13691

Abstract: The rapid reversal of deep neuromuscular blockade (NMB) is important but remains challenging. This study aimed to evaluate the efficacy and safety of adamgammadex versus sugammadex in reversing deep rocuronium‐induced NMB. This multicenter, randomized, phase… read more here.

Keywords: adamgammadex; efficacy; rocuronium induced; safety ... See more keywords

Efficiency and Safety of the Selective Relaxant Binding Agent Adamgammadex Sodium for Reversing Rocuronium-Induced Deep Neuromuscular Block: A Single-Center, Open-Label, Dose-Finding, and Phase IIa Study

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Published in 2021 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2021.697395

Abstract: Background: Rapid reversal of neuromuscular block after surgery and anesthesia is often necessary. Here, we reported the primary efficacy and safety data from a phase IIa study on adamgammadex sodium, a newly developed modified γ-cyclodextrin… read more here.

Keywords: study; phase iia; dose; adamgammadex ... See more keywords