Extended observation of reduced methamphetamine use with combined naltrexone plus bupropion in the ADAPT-2 trial.
Sign Up to like & getrecommendations! Published in 2024 at "Addiction"
DOI: 10.1111/add.16529
Abstract: BACKGROUND AND AIMS A 12-week placebo-controlled, sequential parallel Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use Disorder (ADAPT-2) trial evaluated the effects of extended-release injectable naltrexone plus extended-release oral bupropion (NTX + BUPN) on methamphetamine (MA)… read more here.
Keywords: adapt trial; ntx bupn; trial; methamphetamine use ... See more keywords
Efficient and robust approaches for analysis of sequential multiple assignment randomized trials: Illustration using the ADAPT-R trial.
Sign Up to like & getrecommendations! Published in 2022 at "Biometrics"
DOI: 10.1111/biom.13808
Abstract: Personalized intervention strategies, in particular those that modify treatment based on a participant's own response, are a core component of precision medicine approaches. Sequential multiple assignment randomized trials (SMARTs) are growing in popularity and are… read more here.
Keywords: sequential multiple; adapt trial; assignment randomized; multiple assignment ... See more keywords