Innate and adaptive T cells in influenza disease
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers of Medicine"
DOI: 10.1007/s11684-017-0606-8
Abstract: Influenza is a major global health problem, causing infections of the respiratory tract, often leading to acute pneumonia, life-threatening complications and even deaths. Over the last seven decades, vaccination strategies have been utilized to protect… read more here.
Keywords: adaptive cells; influenza; cells influenza; influenza disease ... See more keywords
CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.020
Abstract: SUMMARY Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK) cells, mechanistic data explaining these phenomena are lacking. Following antibody sensitization, NK cells lacking the Fc receptor (FcR) signaling chain (Δg) acquire adaptive… read more here.
Keywords: alternative signaling; rhesus; functional alternative; primes functional ... See more keywords
Adaptive NK cells undergo a dynamic modulation in response to human cytomegalovirus and recruit T cells in in vitro migration assays
Sign Up to like & getrecommendations! Published in 2022 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-022-01603-y
Abstract: Human cytomegalovirus (HCMV) reactivation remains a relevant complication after hematopoietic stem cell transplantation (HSCT) despite the great progress made in prophylaxis and treatment. Adaptive Natural Killer (NK) cells undergo a persistent reconfiguration in response to… read more here.
Keywords: response; hcmv; hcmv reactivation; adaptive cells ... See more keywords
Innate and adaptive γδ T cells: How, when, and why
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12926
Abstract: γδ T cells comprise the third cell lineage of lymphocytes that use, like αβ T cells and B cells, V(D)J gene rearrangement with the potential to generate a highly diverse T cell receptor (TCR) repertoire.… read more here.
Keywords: innate adaptive; adaptive cells; cell; tcr repertoire ... See more keywords
Redefining Memory: Building the Case for Adaptive NK Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00169-17
Abstract: ABSTRACT Classically, natural killer (NK) cells have been defined by nonspecific innate killing of virus-infected and tumor cells. However, burgeoning evidence suggests that the functional repertoire of NK cells is far more diverse than has… read more here.
Keywords: adaptive cells; building case; case adaptive; memory building ... See more keywords
Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-17-0498
Abstract: Cross-talk between NK cells and Tregs, mediated by IL37 binding its receptor, altered expression of TIM3 and PD-1 on canonical, but not adaptive, NK cells. Increasing adaptive NK cells or blocking Treg suppression mechanisms could… read more here.
Keywords: suppression; canonical cells; treg suppression; cancer ... See more keywords
Evaluation of adaptive NK cells in ovarian cancer patients with cytomegalovirus (CMV) reactivation and systemic inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e18062
Abstract: e18062Background: Cytomegalovirus (CMV) is a common infection associated with increased inflammation (c-reactive protein (CRP) upon reactivation during immunosuppression. CMV infection has been ass... read more here.
Keywords: cells ovarian; inflammation; cytomegalovirus cmv; evaluation adaptive ... See more keywords
Biology and Clinical Relevance of HCMV-Associated Adaptive NK Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.830396
Abstract: Natural killer (NK) cells are an important component of the innate immune system due to their strong ability to kill virally infected or transformed cells without prior exposure to the antigen (Ag). However, the biology… read more here.
Keywords: adaptive cells; relevance hcmv; biology clinical; clinical relevance ... See more keywords
The Frequency and Function of NKG2C+CD57+ Adaptive NK Cells in Cytomagalovirus Co-Infected People Living with HIV Decline with Duration of Antiretroviral Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15020323
Abstract: Human cytomegalovirus (CMV) infection drives the expansion and differentiation of natural killer (NK) cells with adaptive-like features. We investigated whether age and time on antiretroviral therapy (ART) influenced adaptive NK cell frequency and functionality. Flow… read more here.
Keywords: adaptive cells; antiretroviral therapy; frequency; living hiv ... See more keywords