Articles with "adaptive commensurate" as a keyword



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Optimizing interim analysis timing for Bayesian adaptive commensurate designs.

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Published in 2019 at "Statistics in medicine"

DOI: 10.1002/sim.8414

Abstract: In developing products for rare diseases, statistical challenges arise due to the limited number of patients available for participation in drug trials and other clinical research. Bayesian adaptive clinical trial designs offer the possibility of… read more here.

Keywords: interim analysis; bayesian adaptive; optimizing interim; adaptive commensurate ... See more keywords