Immunomodulatory Peptides for Tumor Treatment
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400512
Abstract: Peptides exhibit various biological activities, including biorecognition, cell targeting, and tumor penetration, and can stimulate immune cells to elicit immune responses for tumor immunotherapy. Peptide self‐assemblies and peptide‐functionalized nanocarriers can reduce the effect of various… read more here.
Keywords: immune cells; peptides tumor; tumor immunotherapy; adaptive immune ... See more keywords
Chemotherapy‐Enabled Colorectal Cancer Immunotherapy of Self‐Delivery Nano‐PROTACs by Inhibiting Tumor Glycolysis and Avoiding Adaptive Immune Resistance
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202309204
Abstract: The chemo‐regulation abilities of chemotherapeutic medications are appealing to address the low immunogenicity, immunosuppressive lactate microenvironment, and adaptive immune resistance of colorectal cancer. In this work, the proteolysis targeting chimera (PROTAC) of BRD4 (dBET57) is… read more here.
Keywords: colorectal cancer; cancer; adaptive immune; immune resistance ... See more keywords
Dysfunctions of innate and adaptive immune tumor microenvironment in Waldenström macroglobulinemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34405
Abstract: Waldenström macroglobulinemia (WM) is a rare subtype of non‐Hodgkin lymphoma characterized by malignant lymphoplasmacytic cells in the bone marrow (BM). To dissect the pathophysiology of WM, we evaluated clonal cells by mapping of B cell… read more here.
Keywords: waldenstr macroglobulinemia; tumor microenvironment; innate adaptive; adaptive immune ... See more keywords
Recent insights into innate and adaptive immune responses to Giardia.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in parasitology"
DOI: 10.1016/bs.apar.2019.07.004
Abstract: Infection with Giardia produces a wide range of clinical outcomes. Acutely infected patients may have no overt symptoms or suffer from severe cramps, diarrhea, nausea and even urticaria. Recently, post-infectious irritable bowel syndrome and chronic… read more here.
Keywords: recent insights; infection; responses giardia; immune responses ... See more keywords
Adaptive immune responses to SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Drug Delivery Reviews"
DOI: 10.1016/j.addr.2021.02.009
Abstract: This review focuses on adaptive immune responses against SARS-CoV-2, the coronavirus that causes COVID-19. A great deal of work has been accomplished in a very short period of time to describe adaptive immune responses and… read more here.
Keywords: adaptive immune; responses sars; infection; immune responses ... See more keywords
Role of Aeromonas sp. involving in adaptive immune response of adult Lethenteron reissneri
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.736120
Abstract: Abstract Identifying the intestinal microorganisms involved in host immune functions could supply information for understanding the interaction between microbes and the host. The composition and comparison of the intestinal bacterial community in larval and adult… read more here.
Keywords: adaptive immune; adult; reissneri; adult reissneri ... See more keywords
In vivo imaging of adaptive immune responses to viruses.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2017.12.002
Abstract: Viral infections represent a major threat for mankind. The adaptive immune system plays a key role in both viral clearance and disease pathogenesis, and, accordingly, understanding how lymphocytes interact with different viruses is critical to… read more here.
Keywords: adaptive immune; microscopy; responses viruses; immune responses ... See more keywords
The involvement of TNF-α and TNF-β as proinflammatory cytokines in lymphocyte-mediated adaptive immunity of Nile tilapia by initiating apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103884
Abstract: Tumor necrosis factors (TNFs) are pleiotropic cytokines with important functions in homeostasis and disease pathogenesis. Recent advances have shown that TNFs are also involved in the regulation of adaptive immune responses. However, the knowledge about… read more here.
Keywords: adaptive immune; tnf; tnf tnf; adaptive immunity ... See more keywords
Gut-derived Shewanella induces the differentially expressed proteins in leukocytes of Lampetra japonica.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2021.104123
Abstract: Lampreys, one of the most basal jawless vertebrates, are an excellent animal model for investigating vertebrate evolution, embryonic development, and the origin of adaptive immunity. Gut-derived Shewanella strain was isolated and then proved to induce… read more here.
Keywords: adaptive immune; derived shewanella; expressed proteins; gut derived ... See more keywords
Understanding the increased risk of infections in diabetes: innate and adaptive immune responses in type 1 diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154795
Abstract: AIMS Patients with diabetes have a higher incidence of infections with Candida albicans, Staphylococcus aureus and Mycobacterium tuberculosis, yet factors contributing to this increased risk are largely unknown. We hypothesize that altered innate and adaptive… read more here.
Keywords: adaptive immune; production; stimulation; increased risk ... See more keywords
Mechanistic understanding of innate and adaptive immune responses in SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2021.04.021
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have triggered global pandemic that continue to impact adversely human health. New understanding has emerged about the innate and adaptive immune responses elicited in SARS-CoV-2 infection.… read more here.
Keywords: sars cov; cov infection; adaptive immune; immune responses ... See more keywords