Positive selection of IL‐33 in adaptive immunity of domestic Chinese goats
Sign Up to like & getrecommendations! Published in 2017 at "Ecology and Evolution"
DOI: 10.1002/ece3.2813
Abstract: Abstract The identification of the candidate genes that play key role in phenotypic variation in livestock populations can provide new information about evolution and positive selection. IL‐33 (71954) (Interleukin) gene is associated with the increased… read more here.
Keywords: positive selection; selection; selection adaptive; adaptive immunity ... See more keywords
Inhibition of Tumor-Associated Macrophages by trabectedin improves the anti-tumor adaptive immunity in response to anti-PD-1 therapy.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of immunology"
DOI: 10.1002/eji.202149379
Abstract: A considerable proportion of cancer patients are resistant or only partially responsive to immune checkpoint blockade immunotherapy. Tumor-Associated Macrophages (TAMs) infiltrating the tumor stroma suppress the adaptive immune responses and hence promote tumor immune evasion.… read more here.
Keywords: associated macrophages; tumor associated; anti tumor; adaptive immunity ... See more keywords
Notch signaling at the crossroads of innate and adaptive immunity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ri0520-138r
Abstract: Notch signaling is an evolutionarily conserved cell‐to‐cell signaling pathway that regulates cellular differentiation and function across multiple tissue types and developmental stages. In this review, we discuss our current understanding of Notch signaling in mammalian… read more here.
Keywords: notch; innate adaptive; adaptive immunity; notch signaling ... See more keywords
Adaptive Immunity and the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer treatment and research"
DOI: 10.1007/978-3-030-38862-1_4
Abstract: The adaptive immune response is a 500-million-year-old (the "Big Bang" of Immunology) collective set of rearranged and/or selected receptors capable of recognizing soluble and cell surface molecules or shape (B cells, antibody), endogenous and extracellular… read more here.
Keywords: immunity tumor; adaptive immunity; tumor microenvironment; immunology ... See more keywords
Effects of Glycolipid Rhodococcus Biosurfactant on Innate and Adaptive Immunity Parameters In Vivo
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4172-0
Abstract: The glycolipid biosurfactant complex from actinobacterium Rhodococcus ruber IEGM 231 inhibits the innate and adaptive immunity parameters after intraperitoneal and intramuscular injection. Marked suppression of antibody production, bactericidal potential, and production of proinflammatory cytokines by… read more here.
Keywords: immunity parameters; effects glycolipid; adaptive immunity; innate adaptive ... See more keywords
Reproduction compromises adaptive immunity in a cyprinid fish
Sign Up to like & getrecommendations! Published in 2017 at "Ecological Research"
DOI: 10.1007/s11284-017-1467-y
Abstract: Vertebrates differ in their ability to mount an adaptive immune response to novel antigens. Bioenergetic resources available to an organism are finite; investment in reproduction compromises immune function and may therefore affect critical life history… read more here.
Keywords: reproduction; response; cyprinid fish; reproduction compromises ... See more keywords
What Controls the Acute Viral Infection Following Yellow Fever Vaccination?
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-017-0365-3
Abstract: Does target cell depletion, innate immunity, or adaptive immunity play the dominant role in controlling primary acute viral infections? Why do some individuals have higher peak virus titers than others? Answering these questions is a… read more here.
Keywords: yellow fever; acute viral; immunity; adaptive immunity ... See more keywords
Complex Changes in the Innate and Adaptive Immunity Accompany Progressive Degeneration of the Nigrostriatal Pathway Induced by Intrastriatal Injection of 6-Hydroxydopamine in the Rat
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicity Research"
DOI: 10.1007/s12640-017-9712-2
Abstract: We investigated changes in innate and adaptive immunity paralleling the progressive nigrostriatal damage occurring in a neurotoxic model of Parkinson’s disease (PD) based on unilateral infusion of 6-hydroxydopamine (6-OHDA) into the rat striatum. A time-course… read more here.
Keywords: immunity; time; changes innate; adaptive immunity ... See more keywords
Immunodeficiencies at the Interface of Innate and Adaptive Immunity
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Immunology"
DOI: 10.1016/b978-0-7020-6896-6.00036-3
Abstract: Abstract In the last 20 years, new primary immunodeficiencies (PIDs) affecting the immunity mediated by interferon (IFN)-γ, IFN-α/β-λ, Toll and interleukin-1 receptor (TIR) domain nuclear factor (NF)-κB, Toll-like receptor (TLR)-3 pathway, and interleukin (IL)-17 have… read more here.
Keywords: immunodeficiencies interface; immunity; immunology; innate adaptive ... See more keywords
Drosophilosophical: Re-thinking Adaptive Immunity in the Fly
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.03.032
Abstract: For decades, flies have been a model for innate immunity. In this issue of Cell, Tassetto et al. describe a mechanism for antiviral RNAi spreading that parallels mammalian adaptive immunity through reverse-transcribed vDNA circles and the… read more here.
Keywords: immunity fly; immunity; drosophilosophical thinking; thinking adaptive ... See more keywords
Modulation of innate and adaptive immunity by P2X ion channels.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2018.03.026
Abstract: Extracellular ATP is a major component of the inflammatory microenvironment where it accumulates following cell and tissue injury but also as a consequence of non-lytic release from activated inflammatory cells. In the inflammatory microenvironment ATP… read more here.
Keywords: p2x; ion; adaptive immunity; innate adaptive ... See more keywords