Glucose starvation as a selective tool for the study of adaptive mutations in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2016.11.007
Abstract: Mutations not only arise in proliferating cells but also in resting - thus non-replicating - cells. Such stationary-phase mutations may occasionally enable an escape from growth repression and e.g. contribute to cancerogenesis or development of… read more here.
Keywords: study adaptive; adaptive mutations; saccharomyces cerevisiae; glucose starvation ... See more keywords
Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations
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DOI: 10.1093/molbev/msad010
Abstract: Abstract Experimental evolution studies have shown that weak antibiotic selective pressures (i.e., when the antibiotic concentrations are far below the minimum inhibitory concentration, MIC) can select resistant mutants, raising several unanswered questions. First, what are… read more here.
Keywords: antibiotic concentrations; adaptive mutations; low antibiotic; resistance ... See more keywords
Detecting Potentially Adaptive Mutations from the Parallel and Fixed Patterns in SARS-CoV-2 Evolution
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DOI: 10.3390/v14051087
Abstract: Early identification of adaptive mutations could provide timely help for the control and prevention of the COVID-19 pandemic. The fast accumulation of SARS-CoV-2 sequencing data provides important support, while also raising a great challenge for… read more here.
Keywords: potentially adaptive; parafix mutations; adaptive mutations; detecting potentially ... See more keywords