Microenvironment-adaptive nanomedicine MXene promotes flap survival by inhibiting ROS cascade and endothelial pyroptosis
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DOI: 10.1186/s12951-025-03343-9
Abstract: In the field of large-area trauma flap transplantation, preventing avascular necrosis remains a critical challenge. Key mechanisms for improving flap viability include angiogenesis promotion, oxidative stress inhibition, and cell death prevention. Recently, two-dimensional ultrathin Ti3C2TX… read more here.
Keywords: flap survival; pyroptosis; mxene; adaptive nanomedicine ... See more keywords