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Published in 2021 at "British Journal of Nutrition"
DOI: 10.1017/s0007114521001094
Abstract: Abstract Adaptive thermogenesis (AT) has been proposed to be a compensatory response that may resist weight loss (WL) and promote weight regain. This systematic review examined the existence of AT in adults after a period… read more here.
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Published in 2017 at "Nature medicine"
DOI: 10.1038/nm.4316
Abstract: Adaptive thermogenesis is the process of heat generation in response to cold stimulation. It is under the control of the sympathetic nervous system, whose chief effector is the catecholamine norepinephrine (NE). NE enhances thermogenesis through… read more here.
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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06462-0
Abstract: Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear. Here we identify the neuropeptide FF receptor-2 (NPFFR2)… read more here.
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Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13418
Abstract: There is evidence emerging that exposure to cold temperatures enhances alternative activation of macrophages in white adipose tissue (WAT), which promotes adipocyte beiging and adaptive thermogenesis. Although we recently reported that NAD+‐dependent deacetylase sirtuin 6… read more here.
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Published in 2021 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.67.99
Abstract: Increasing adaptive thermogenesis through the activation of brown adipose tissue (BAT) is a promising practical strategy for preventing obesity and related disorders. Ingestion of a single dose of 40 mg of an extract of Grains… read more here.
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Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00517
Abstract: Homeothermic mammals including humans produce heat (also termed thermogenesis) inside their body to maintain constant body temperature. It has been shown that thermogenesis is elevated by several external factors; prominent being cold, diet, and physical… read more here.
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Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1124408
Abstract: Brown and beige adipose tissues regulate body energy expenditure through adaptive thermogenesis, which converts energy into heat by oxidative phosphorylation uncoupling. Although promoting adaptive thermogenesis has been demonstrated to be a prospective strategy for obesity… read more here.
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Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11020124
Abstract: Thermogenesis is an energy demanding process by which endotherms produce heat to maintain their body temperature in response to cold exposure. Mitochondria in the brown and beige adipocytes play a key role in thermogenesis, as… read more here.
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Published in 2022 at "Theranostics"
DOI: 10.7150/thno.77102
Abstract: Brown and beige fat protect against cold environments and obesity by catabolizing stored energy to generate heat. This process is achieved by controlling thermogenesis-related gene expression and the development of brown/beige fat through the induction… read more here.
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Published in 2022 at "eLife"
DOI: 10.7554/elife.81996
Abstract: Thyroid hormone (T3) and its nuclear receptors (TR) are important regulators of energy expenditure and adaptive thermogenesis, notably through their action in the brown adipose tissue (BAT). However, T3 acts in many other peripheral and… read more here.