Adaptive trial designs for spinal cord injury clinical trials directed to the central nervous system.
Sign Up to like & getrecommendations! Published in 2020 at "Spinal cord"
DOI: 10.1038/s41393-020-00547-8
Abstract: STUDY DESIGN Narrative review. PURPOSE To provide an overview of adaptive trial designs, and describe how adaptive methods can address persistent challenges encountered by randomized controlled trials of people with spinal cord injury (SCI). RESULTS… read more here.
Keywords: adaptive trial; trial; trial designs; adaptive methods ... See more keywords
Protocol for a bandit-based response adaptive trial to evaluate the effectiveness of brief self-guided digital interventions for reducing psychological distress in university students: the Vibe Up study
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DOI: 10.1101/2022.12.05.22283129
Abstract: Introduction Meta-analytical evidence confirms a range of interventions, including mindfulness, physical activity and sleep hygiene, can reduce psychological distress in university students. However, it is unclear which intervention is most effective. Artificial intelligence (AI)-driven adaptive… read more here.
Keywords: distress; adaptive trial; psychological distress; university students ... See more keywords
A prospective, iterative, adaptive trial of carfilzomib‐based desensitization
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DOI: 10.1111/ajt.15613
Abstract: Proteasome inhibitor–based strategies hold promise in transplant but have yielded varying results. Carfilzomib, a second‐generation proteasome inhibitor, may possess advantages over bortezomib, the first‐generation proteasome inhibitors. The purpose of this study was to evaluate the… read more here.
Keywords: adaptive trial; iterative adaptive; based desensitization; desensitization ... See more keywords