Regulation of ASK1 signaling by scaffold and adaptor proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2017.10.003
Abstract: The mitogen-activated protein kinase (MAPK) signaling pathway is a three-tiered kinase cascade where mitogen-activated protein kinase kinase kinases (MAP3Ks) lead to the activation of mitogen-activated protein kinase kinases (MAP2K), and ultimately MAPK proteins. MAPK signaling… read more here.
Keywords: kinase; scaffold adaptor; adaptor proteins; mitogen activated ... See more keywords
Roles and regulation of myosin V interaction with cargo.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2021.100787
Abstract: A major question in cell biology is, how are organelles and large macromolecular complexes transported within a cell? Myosin V molecular motors play critical roles in the distribution of organelles, vesicles, and mRNA. Mis-localization of… read more here.
Keywords: myosin; roles regulation; adaptor proteins; regulation myosin ... See more keywords
Involvement of adaptor proteins in clathrin-mediated endocytosis of virus entry.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105278
Abstract: The first step in the initiation of effective viral infection is breaking through the cytomembrane to enter the cell. Clathrin-mediated endocytosis is a key vesicular trafficking process in which a variety of cargo molecules are… read more here.
Keywords: clathrin mediated; mediated endocytosis; adaptor proteins; involvement adaptor ... See more keywords
Epsin Endocytic Adaptor Proteins in Angiogenic and Lymphangiogenic Signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041165
Abstract: Circulating vascular endothelial growth factor (VEGF) ligands and receptors are central regulators of vasculogenesis, angiogenesis, and lymphangiogenesis. In response to VEGF ligand binding, VEGF receptor tyrosine kinases initiate the chain of events that transduce extracellular… read more here.
Keywords: epsin endocytic; endocytic adaptor; proteins angiogenic; adaptor proteins ... See more keywords
Classification of adaptor proteins using recurrent neural networks and PSSM profiles
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6335-4
Abstract: Adaptor proteins are carrier proteins that play a crucial role in signal transduction. They commonly consist of several modular domains, each having its own binding activity and operating by forming complexes with other intracellular-signaling molecules.… read more here.
Keywords: neural networks; biology; recurrent neural; pssm profiles ... See more keywords
Tks adaptor proteins at a glance
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cell Science"
DOI: 10.1242/jcs.203661
Abstract: ABSTRACT Tyrosine kinase substrate (Tks) adaptor proteins are considered important regulators of various physiological and/or pathological processes, particularly cell migration and invasion, and cancer progression. These proteins contain PX and SH3 domains, and act as… read more here.
Keywords: proteins glance; adaptor proteins; tks adaptor;
Sinner or Saint?: Nck Adaptor Proteins in Vascular Biology
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.688388
Abstract: The Nck family of modular adaptor proteins, including Nck1 and Nck2, link phosphotyrosine signaling to changes in cytoskeletal dynamics and gene expression that critically modulate cellular phenotype. The Nck SH2 domain interacts with phosphotyrosine at… read more here.
Keywords: nck adaptor; vascular biology; biology; nck1 nck2 ... See more keywords